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Professor Øyvind S. Bruland

Professor Øyvind S. Bruland


Textbook on osteosarcoma


Editors: Jaffe, Bruland and Bielack

In essence the scope and intensive coverage of the book provides a historical perspective of the advances made over the past 30 years and emerging concepts and prospects for new diagnostic and therapeutic approaches. This is based upon past experiences and new discoveries. It also provides a unique opportunity for pediatric and adult medical oncologists, physicians in training, orthopedic surgeons, pathologists, radiologists, radiotherapists, oncology nurses and allied professionals involved in the care of pediatric/adolescent patients with osteosarcoma to become acquainted with prevailing methods of treatment and new and evolving concepts and developments.

Click here to view a flyer on the book (Word format)

Click here to view table of contents.

PDFs of the three chapter I have co-authored can be downloaded below:

  • Radiotherapy in osteosarcoma (click here for PDF)
  • Scandinavian Sarcoma Group experience (click here for PDF)
  • Impact of Micrometastases in Classical Osteosarcoma (click here for PDF)

A direct link to this book from Springer Verlag: click here


Management of Osteosarcoma - Behandling av Osteogent Sarkom


Our single institution experience on the outcome of an unselected patient population with osteosarcoma following multimodal treatment was published in Acta Oncologica.

To view the article:
Extremity and Non-Extremity High-Grade Osteosarcoma: The Norwegian Radium Hospital experience during the modern chemotherapy era

Click here for a pdf


Acta Orthop., 80 Suppl 334, 60-66 (2009)

Scandinavian experience in classical osteosarcoma Results of the SSG XIV protocol


Click here to download article (in PDF format)


Osteosarcoma Odyssey


During this symposium the current treatment of osteosarcoma was discussed among invited key opinion leaders. The purpose was to highlight the state of the art in oncological therapy and discuss ongoing research projects.
Click here to view my welcome remarks and here to view the Agenda & Scientific Programme.
Click here to view the back cover of the 136-pages Symposium Proceedings (ISBN 82-91929-02-5).
Click here to view the front cover (left) in larger format.

The evolution of osteosarcoma therapy has indeed been a difficult and challenging journey - an exciting adventure, ample with both disappointments and sprectacular rewards. We are still underway; the Odyssey must continue!

Below, I have posted selected chapters from the Proceedings that may be downloaded as pdf-documents by clicking on the respective titles.

Bruland & Pihl: The many faces of osteosarcoma
Norman Jaffe: Osteosarcoma: The beginning of the odyssey
Sæter & Bruland: High-grade osteosarcoma: The scope beyond the "classical" patient.

The COSS-experience was presented by Professor Stefan Bielack. He is currently Director, Department of Pediatrics, Olga Hospital, Stuttgart

Session 4: "Metastatic Osteosarcoma"

Abstracts from this session on the treatment of lung metastases from osteosacoma can be downloaded:

Click here to view the presentation by Ugo Pastorino.
He is currently with The National Cancer Institute in Milan (e.mail:

Click here for the Rizzoli-experience by Bacci et al.

Click here for The Norwegian Radium Hospital experience

(click to enlarge)

In a recent original article in Acta Oncologica, the experience over two decades in the management of primary high-grade bone sarcomas at The Norwegian Radium Hospital was analyzed. Important aspects on referral patterns, prognostic variables, outcome-measures and time-trends were presented for patients with Ewing and osteosarcoma.

Click here for a PDF of the paper

Figure: Osteosarcoma of the distal femur in a young patient treated with pre-operative chemotherapy and a limb-sparing surgical procedure.

The treatment of osteosarcoma has been reviewed in the following paper published i Eur J Cancer:

On the current management of osteosarcoma

Open document (PDF format)

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